Respiratory distress syndrome sometimes exists in new born infants – and it is caused by a lack of surfactant – it makes it very difficult for the baby to breathe because the high fluid tension makes it difficult for the lungs to expand.This contains both I and E (expiratory) neurons, and it is active in forced breathing. The VRG (ventral respiratory group) are also found in the medulla.They are active in every breath, whether quiet or forced. The DRG (Dorsal respiratory group) is a group of neurons in the medulla.These patients will require mechanical ventilation for the rest of their lives (but usually only during sleep). It is also known as primary alveolar hypoventilation. It occurs in 1 in 200,000 live births, but can also occur as a result of trauma to the brainstem, or poliomyelitis. Ondine’s curse – this is a condition where there is damage to the autonomic nervous system such that a person may ‘forget’ to breathe, usually during sleep.However, this can be regulated by conscious activity in the cerebrum. The breathing centre in the medulla co-ordinates all the muscles required for breathing. You cannot continue to breathe if the nervous supply to the muscles is cut off (unlike the heart) because breathing is controlled by skeletal muscle.
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